LOH Research Group @
30th September 2020
Our latest publication in Nature Communications depicts the power of XB catalysis to illicit quantum tunneling in the rate determining proton transfer step of 2-deoxyglycosylations. Check it out! Link
8th March 2019
Our research demonstrating the first case of a multi-stage halogen bond (XB) catalyzed strain-release glycosylation which unravels non-SMO Hedgehog signaling inhibitors is currently online in JACS! Link
3rd October 2018
Our research group’s first independent paper is published currently in Nature Communications! Link
Impressive job by Chunfa for the superb effort spearheading strain-release glycosylations using ultra-low loadings of thiourea.
We are a young and dynamic research group situated at the Technical University of Dortmund and the Max Planck Institut für Molekulare Physiologie. Currently, we are actively involved in synthetic methodology development of noncovalent catalysis in carbohydrate chemistry, for more information on our research, check out our research interest page.
We are always seeking for enthusiastic organic chemists seeking to further their doctoral studies or their post-doctoral research in an exciting and challenging environment. We highly value scientists who show exceptional aptitude for out-of-the-box thinking and aspiring to revolutionize modern synthetic methodologies with a chemical biology outlook. If you are interested in embarking on this adventurous research endeavour with us, feel free to contact Dr. Charles Loh for more information.
For research profile of Dr. Charles Loh, see:
The following funding agencies are gratefully acknowledged for generous funding :